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No.QuestionSubjectLevelStatus
001 During an electrophysiology study the atrioventricular node is located within the triangle of Koch. Which landmark lies at the base of this triangle?Heart chambers and valves · MECEE-PG entrance pattern Anatomy 002 A cardiac surgeon passes a finger through the transverse pericardial sinus to place a clamp. The finger lies behind which structures?Pericardium and mediastinum · MECEE-PG entrance pattern Anatomy 003 After thyroidectomy a schoolteacher from Dharan notices that she can no longer sing high notes, though her speaking voice is otherwise normal. The nerve injured runs with which artery?Head, neck and neuroanatomy · MECEE-PG entrance pattern Anatomy 004 Which compound is the most potent allosteric activator of phosphofructokinase-1 in the liver?Glycolysis · MECEE-PG entrance pattern Biochemistry 005 A 6-month-old infant has fasting hypoglycaemia, massive hepatomegaly, lactic acidosis and hyperuricaemia. Blood glucose does not rise after glucagon. Which enzyme is deficient?Gluconeogenesis and glycogen · MECEE-PG entrance pattern Biochemistry 006 A 19-year-old porter develops painful muscle cramps and dark urine after carrying a heavy load uphill. Blood lactate fails to rise after ischaemic forearm exercise. Which enzyme is deficient?Gluconeogenesis and glycogen · MECEE-PG entrance pattern Biochemistry 007 A newborn develops vomiting, jaundice, hepatomegaly and cataracts soon after starting breast milk. Reducing substances other than glucose are present in the urine. Which enzyme is most likely deficient?HMP shunt and other sugars · MECEE-PG entrance pattern Biochemistry 008 After a carbohydrate-rich meal, newly synthesised fatty acids in the liver are not immediately oxidised. Malonyl-CoA prevents this by inhibiting which enzyme?Lipids and amino acids · MECEE-PG entrance pattern Biochemistry 009 Which study design is best suited to studying the health effects of a rare exposure, such as work in a particular chemical factory?Epidemiological study designs · MECEE-PG entrance pattern Community Medicine 010 A study finds that people who drink coffee have a higher risk of lung cancer. Coffee drinkers are also more likely to smoke, and smoking causes lung cancer. In this study, smoking is acting as what?Epidemiological study designs · MECEE-PG entrance pattern Community Medicine 011 A new drug is introduced that prolongs the life of patients with a chronic disease but does not cure it. If incidence stays the same, what happens to the prevalence of the disease?Measures of disease and association · MECEE-PG entrance pattern Community Medicine 012 In a case-control study, 40 of 50 cases and 20 of 50 controls had been exposed to the risk factor. What is the odds ratio?Measures of disease and association · MECEE-PG entrance pattern Community Medicine 013 A screening test is applied to 500 people, of whom 50 have the disease. It is positive in 45 of the diseased and in 45 of the non-diseased. What is the positive predictive value of the test?Screening · MECEE-PG entrance pattern Community Medicine 014 After a screening programme begins, patients appear to survive longer from the time of diagnosis, yet the age at which they die is unchanged. Which bias explains this?Screening · MECEE-PG entrance pattern Community Medicine 015 A school programme encourages young children to adopt healthy eating and regular exercise so that risk factors for heart disease never develop. Which level of prevention is this?Levels of prevention · MECEE-PG entrance pattern Community Medicine 016 In hypothesis testing, what is a type I error?Biostatistics · MECEE-PG entrance pattern Community Medicine 017 Which molecule, concentrated at the junctions between endothelial cells, mediates transmigration (diapedesis) of leukocytes?Acute inflammation · MECEE-PG entrance pattern Pathology 018 An infant has delayed separation of the umbilical cord, recurrent bacterial skin infections without pus formation and a persistently high neutrophil count. A defect in which molecule is most likely?Acute inflammation · MECEE-PG entrance pattern Pathology 019 A 5-year-old boy has recurrent abscesses caused by Staphylococcus aureus and Aspergillus. The nitroblue tetrazolium test shows no reduction of the dye. Which enzyme is defective?Acute inflammation · MECEE-PG entrance pattern Pathology 020 In the intrinsic (mitochondrial) pathway of apoptosis, which molecule is released from mitochondria into the cytosol to activate caspase-9?Cell injury and adaptation · MECEE-PG entrance pattern Pathology