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No.QuestionSubjectLevelStatus
021 High-risk human papillomavirus types 16 and 18 cause cervical carcinoma partly through their E6 protein. What does E6 do?Neoplasia · MECEE-PG entrance pattern Pathology 022 In an anaesthetised animal pretreated with phentolamine, an intravenous injection of adrenaline produces a fall in blood pressure instead of a rise. Which action of adrenaline explains this?Adrenergic agonists · MECEE-PG entrance pattern Pharmacology 023 Clonidine lowers blood pressure by acting on which receptor?Adrenergic agonists · MECEE-PG entrance pattern Pharmacology 024 A patient with phaeochromocytoma is being prepared for surgery. Which drug should be started first?Adrenergic blockers · MECEE-PG entrance pattern Pharmacology 025 Which drug is eliminated by zero-order kinetics at commonly encountered plasma concentrations?General pharmacology · MECEE-PG entrance pattern Pharmacology 026 The loading dose of a drug needed to achieve a target plasma concentration depends primarily on which parameter?General pharmacology · MECEE-PG entrance pattern Pharmacology 027 The upstroke (phase 0) of the action potential in a sinoatrial node cell is produced mainly by which current?Cardiac electrophysiology · MECEE-PG entrance pattern Physiology 028 Which current is chiefly responsible for the slow diastolic depolarisation (phase 4) of sinoatrial node cells?Cardiac electrophysiology · MECEE-PG entrance pattern Physiology 029 If the radius of an arteriole is halved while all other factors remain constant, how does its resistance to flow change?Cardiac output and haemodynamics · MECEE-PG entrance pattern Physiology 030 In which phase of the cardiac cycle is blood flow through the left coronary artery greatest?Cardiac output and haemodynamics · MECEE-PG entrance pattern Physiology 031 A man consumes 250 mL of oxygen per minute. His arterial oxygen content is 200 mL/L and his mixed venous oxygen content is 150 mL/L. What is his cardiac output by the Fick principle?Cardiac output and haemodynamics · MECEE-PG entrance pattern Physiology